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VOL. 1, ISSUE 1 (2025)
Neuronevus: Clinical and dermoscopic features – A Descriptive Study
Authors
Amina Flissi
Abstract
Neuronevus is a rare
benign melanocytic lesion characterized by neural differentiation, often posing
diagnostic challenges due to its varied clinical and dermoscopic presentations.
This descriptive study aims to evaluate and characterize the clinical and
dermoscopic features of neuronevi to aid in better recognition and
differentiation from other melanocytic and non-melanocytic lesions. We
retrospectively analyzed cases diagnosed as neuronevus over a five-year period
across two tertiary dermatology centers. Clinical parameters including patient
demographics, lesion morphology, anatomical location, and evolution were
recorded. Dermoscopic evaluation was performed using polarized dermoscopy, with
findings assessed by two independent dermatologists. The most frequent clinical
presentation was a dome-shaped, skin-colored to lightly pigmented papule or
nodule, predominantly occurring in younger individuals. Dermoscopically, common
features included structureless areas, peripheral globules, and homogeneous
pigmentation, with some lesions showing atypical vascular patterns. No
malignant transformations were observed during the follow-up period. Our
findings suggest that while neuronevi may resemble common melanocytic nevi or
neurofibromas, certain dermoscopic features—particularly the absence of a
pigment network and the presence of specific globular or structureless patterns—may
assist in differentiation. Early and accurate recognition of neuronevus can
prevent unnecessary excision and reduce patient anxiety. Further prospective
studies are recommended to validate these findings.
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Pages:6-10
How to cite this article:
Amina Flissi "Neuronevus: Clinical and dermoscopic features – A Descriptive Study". World Journal of Medicine Research , Vol 1, Issue 1, 2025, Pages 6-10
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